@ijones98280, here's an excerpt from the American Cancer Society about the significance of finding out if a tumor is P16 positive or not

HPV (p16) testing https://www.cancer.org/cancer/types/oral-cavity-and-oropharyngeal-cancer/detection-diagnosis-staging/how-diagnosed.html
"For cancers of the throat, the biopsy samples are often tested (for the p16 protein) to see if HPV infection is present. This is a key part of staging (finding out if and how much the cancer has spread) and is considered when making treatment decisions for oropharyngeal cancer. This information can also help the doctor predict the probable course of the cancer, because people whose cancers are linked to HPV tend to do better than those whose cancers are not."

Here are a couple of related discussion where you can connect with other members with a similar diagnosis:
- Standard Procedure for Stage 1 OPSCC P16+?
https://connect.mayoclinic.org/discussion/standard-procedure-for-stage-1-opscc-p16/
- HPV P16 positive cancer
https://connect.mayoclinic.org/discussion/hpv-p16-positive-cancer/
See all https://connect.mayoclinic.org/group/head-neck-cancer/?search=p16&index=discussions

What is the next step for you?