Do BC survivors have higher risk of ovarian, uterine, cervical cancer?

I had a double mastectomy for stage 1, 7 mm found on routine mammogram, ER/PR+ HER2-, BRCA2+ 11 years ago. Follow-up was a breast MRI at 1 year, ultrasound every 3 months year one then every 6 mo years 2-5, then once a year. I was told they can never get 100% of the breast tissue. About 2% remains. I had a 3-5% chance of recurrence. I had a 1.2 cm recurrence in my chest wall, Ki-67 50%, at 7 years. I felt the lump myself two days before my annual ultrasound. Had tumor resection with a positive margin, 37 radiation treatments, now on Letrozole and Kisqali for 3.5 years so far and forever so long as they work. Follow-up is CT scans of chest, abdomen and pelvis every 6 months. It was every 3 months the first year. Prayers for all.

I had a mastectomy and will no longer have a mammogram but an US at 1 year. I am not sure yet about an MRI. I had clear lymph nodes-3 sentinels. Difference of what we have, what hospital treats us and what doctor. IF you think you want test, check with the doctor. Here on Mayo you may just read in the breast blogs what they do.

thank you for sharing, thats interesting as i was told that i still need mammo (even tho ILC rarely ever shows there) because other BCs could still show up and are often only seen on mammo. The place I'm at will not do ultrasound screenings at all. Only targeted ultrasound if there is something on a mammo. Mine was very similar - I was also told 8% recur in 10y, that was per Oncotype. Altho I was told by another onco that Oncotype is not valid for ILC, that it really only is accurate for ductal.

My path report only lists the hormone receptors, they said they wont do genetic/somatic mutation testing on the tumor, not sure why. I thought the genetic mutations in the tumor itself may influence recurrence but they told me only the genetic mutations I was born with would influence recurrence. I've been looking for some solid research / info about whether or not having a hormone receptor BC influences if you're higher risk for a gyn cancer but I can't find much. Amer cancer society says a family history of colon cancer can raise your risk of uterine cancer but I had a gyne onco tell me thats false, which seems odd.

I havent had genetic testing yet but strongly considering it. My onco told me it "doesn't matter" if I want to have BSO or stay on ovarian suppression and they said there's "no reason" to remove uterus and cervix. However I found this link on MD Anderson saying that BC survivors are at higher risk for uterine cancer, altho they dont clarify if thats only for BC survivors who take tamoxifen. https://www.mdanderson.org/publications/focused-on-health/uterine-cancer--what-s-your-risk-.h14-1592991.html I definitely want to do a BSO to stop the shots, but struggling with the uterus/cervix removal because I've heard of so many women having prolapse or incontinence issues with a few years of a full hysterectomy.

If you are considering removing ovaries. Then do ovaries and phyloipian tubes. That will not a total historectomy, but yes you can have other complications with it because you are not only stopping the production of estrogen, but also testosterone etc. Things the body needs for other organs to function and the body itself.

I am er pr positive and need to take tamozx and lupron. I can't take the lupron it made me a mentally out of control this was 4 months of it. I am looking into a full hysterectomy. Breast surg said same thing prolapse and incontinence, but I'm scared to keep my ovaries. If I get rid of it all I will have peace of mind knowing ovarian and uterine cancer will not be in ny future. No idea what too do.

@positivity1 I'm with you on stopping lupron - the shots make me feel ill for at least 3 days each month. I figure if I add all that up month after month I could've had the surgery to remove ovaries and recovered by now! I started out thinking I will do ovaries, tubes, uterus and cervix but I'm really getting too concerned about prolapse and incontinence, especially since I read that just taking an AI alone increases incontinence because of no estrogen. Since I don't have any risk factors for uterine (except BC history), I'm leaning towards only ovaries and tubes for now and then maybe years later doing uterus + cervix if I want to reduce risk. I just hope they would do the uterus + cervix later (ie insurance coverage also) if I want it in 5 or 10 years without any symptoms.

I spoke with my oncologist and I have to go back on lupron and get on mental health meds. Ugh not thrilled. Told I would be thee same way if I had my ovaries taken out. So frustrating

I know they say that lupron is same as surgical/natural menopause side effects but I really do wonder if that is the case. Surgical/natural menopause doesn't have actual drug side effects and its well known that Lupron has its own side effects. Just my 2 cents... For me I can't see doing the shots for years and years so I'm going to go for the ovary removal at some point.