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Is this normal on ADT? Body hair gone

Prostate Cancer | Last Active: Sep 23 2:56pm | Replies (76)
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@jeffmarc

Checked with my friend who went to the PCRI conference and sure enough taking Zytiga for more than four years also causes neuroendocrine cancer, which is pretty much not treatable yet.

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northoftheborder | @northoftheborder | Sep 19 6:06pm

Thanks for that info. Do you have a link to the study?

I'll mention it to my RO on Monday, but even before seeing the study I'm guessing it's far too early to talk about causation; it probably detected a small-but-statistically significant correlation that would need to be investigated further. I'd also have to know the type(s) of PCa where they found the apparent correlation (advanced or early? non-metastatic, oligometastatic, or high-load metastatic? etc).

The only relevant study I could find with my own web search was one about using Apalutamide to *treat* neuroendocrine cancer successfully, which shows how tricky it can be drawing conclusions from isolated studies.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11157388/

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