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Evenity - My Email to FDA

Osteoporosis & Bone Health | Last Active: Sep 23, 2024 | Replies (73)

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@marymj7

I weigh 118 lbs and took full dose for three months, which means I have actually had about three and two-thirds dose. I am trying to figure out the time frame regarding when this drug will be out of my system. I have to quit because I need major oral surgery and want to be sure the drug is gone. The drug is said to reach a steady state at month three and has a non linear elimination. Anyone have any ideas?

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Replies to "I weigh 118 lbs and took full dose for three months, which means I have actually..."

@marymj7 I don't know if anyone knows how anti-resorptive Evenity is at that point. Ben Leder has a chart on his you tube video "Combining and Sequential Approaches to Osteroporosis." It is a mild anti-resorptive, I was told. Evenity has only been around since 2019. Do they even know the risk for oral surgery? Is it hypothetical, anecdotal or proven in studies?

The half life at 3 months is 12.8 days so half is gone by that time.
https://www.drugs.com/medical-answers/what-happens-when-you-stop-evenity-3577578/
I was told that Evenity continues to "mineralize" for two months.