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PMR and prednisone

Polymyalgia Rheumatica (PMR) | Last Active: Sep 24 5:09pm | Replies (33)

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@dadcue

Was your prescription written 5 mg of Prednisone 2-3 times per day as needed? Is your prescription for hydrocortisone?

The typical starting dose of Prednisone for PMR is 15 mg every day taking the entire dose every morning with food.

"Joint guidelines from the European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR) conditionally recommend starting corticosteroid therapy with 12.5-25 mg/day of prednisone or the equivalent. [30] A systematic examination of the peer-reviewed literature, which included 30 studies, found that most patients seemed to achieve remission of PMR with a starting dose of prednisone at 15 mg/day. A slow tapering of the prednisone, less than 1 mg/month, was associated with fewer relapses. Once prednisone is tapered to 10 mg/day, a further slow taper by 1 mg every 2 months until treatment discontinuation was associated with optimal control of disease activity. [43]"
https://emedicine.medscape.com/article/330815-treatment?form=fpf
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A side effect of Prednisone is increased blood glucose levels. The link above has several pages that discuss diet and exercise as well as how you should taper off Prednisone.

There is no single best way or correct way to taper off Prednisone no matter what you may read. There are too many factors to consider for someone to suggest they know the best way to taper. There is no research that supports any tapering strategy that works better except for a "slow taper." Nobody knows how slow because it is all based on your own individual symptoms and whether or not you relapse.

I must have done everything wrong because I was on Prednisone to treat PMR for more than 12 years. It took that long until my rheumatologist found a better treatment option for me.

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Replies to "Was your prescription written 5 mg of Prednisone 2-3 times per day as needed? Is your..."

Yes 2 to 3 5mg per day. I didn't know I had to taper. Thank you fir the information.

Thank you! My prescription was 2 to 3 5mg of prednisone a day. I did ask my physician if I could divide it over the day and he had no objections. I am glad I found this site. I appreciate your input.