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@cherziggy

I’m on the fence about trying a 3rd AI. First two weren’t tolerable. Please share good or bad experiences. Thank you!

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Replies to "I’m on the fence about trying a 3rd AI. First two weren’t tolerable. Please share good..."

Switching manufacturers and then to brand name helped me. I know everyone is different! Which ones have you tried and what are you about to try?

I tried anastrozole- did not work. I am on exestamine- joint aches and sleep issue, went off for a bit but back on with less side effects… I also added seeing an acupuncturist ( she’s also a oncologist) which has helped the side effects - she also recommended some supplements. I also walk, healthy yoga and a breathing yoga which has really work! I am not joint ache free, but everything has helped. I’m 61 . I’m okay with my “new” normal.

My oncology nurse (after much cajoling on her part) got me to try osteo bi flex for the horrible joint pain I was experiencing. Much to my surprise, after about two months, the pain was so much better. You may want to give it a try 🌹

I started exemestane again today after taking a two week break. I’m keeping my fingers crossed!
Congrats to you friend!
Thank you for the feedback! 🤗

I've been on Xeloda, Anastrozole and am now taking Exemestane I find they are pretty much all the same. I do not get alot of the aches and pains that women have problems with, but it definitely affects your moods. ALL of them. And they make you very tired. I am also having some weight gain issues with the Exemestane. Best of luck to you.

I believe there is a lot to be said about trying different types of AI's including different manufacturers who may also use different fillers.
But something to keep in mind is the drug is meant to suppress estrogen production. If you research how estrogen works in your body, you'll get a better idea of what to expect simply because the drug is working. Weight gain, for one, is possible because of the lowered estrogen level, not the drug per say. There's also elevated lipid levels, moodiness, insomnia, and more. It's the loss of the estrogen that may be to blame. As to joint pain, I was almost literally crippled by knee pain, but adding collagen supplements had huge results. I also found that when I tried a lower dosage that I had serious jaw pain (from Prolia?) that improved with a higher dosage. Everyone is different and will react differently so you just keep experimenting. This forum is such a great place to get those ideas.

I have always had weight issues… just chubby - I would have to say possibly- if that makes sense. I gained about 5-10 pounds during treatments. And currently stay there or 5 lbs more. Hope that helps. I honestly haven’t worked on losing weight. I am currently eating very healthy.