1. < Osteoporosis & Bone Health

How many doses does an 80mcg Tymlos pen have on average?

Posted by healthmatters @healthmatters, Sep 6 8:25pm

And has anyone ever considered injecting near the buttocks? I ask this because I have read some persons reporting an increase of belly fat when they inject Tymlos on their belly.

I did search and read that someone was injecting near their buttock area.

I pondered the many reasons injecting near the buttocks may or may not work - reaching the area to inject easily, vascularity, different or slower absorption? I also wondered if the absorption needs to be immediate or delayed to work and if a slow release might diminish the fast heart rate some of us might experience.

So much to consider!

I mean once the medication is under the skin where does it have to go but through the subcutaneous fat on the belly's and buttock's capillaries.

I would think the buttocks are not as highly/densely vascularized at the belly fat but .... is that the case?

As far as reaching the area, and IF the absorption is complete even if slow, I would find a way to inject in the buttocks if it would avoid the belly from becoming fat. If I did it, I would actually alternate sides.

Maybe there is a study which can explain it.

I am 5'6" and 102 pounds so there is not much fat on my buttocks ;( - it would seem it would absorb there just as well as my belly.

Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.

windyshores | @windyshores | Sep 8 10:13am
In reply to @dooshie "Each 80mcg pen, if fully injected, is good for 30 days, although there was always a..." + (show)
@dooshie

Each 80mcg pen, if fully injected, is good for 30 days, although there was always a bit left in the pen at the end of that time period. I always injected in my belly, rotating the area. I did encounter increased belly fat with Tymlos but I had a 15% gain in my spine and 3.5% in my hips after 2 years, so I’ll deal with the extra fat for now. I finished my protocol in June and the belly fat is still there. Hoping it decreases as time goes on. With osteo and the med choices, there are positives and negatives. This journey is full of decisions and we do the best we can with what we are given. Every drug comes with potential side effects. We are all different and if a med causes a side effect, we have to weigh the risks versus the benefits. I’m glad I stuck with the full 2-year protocol. Wishing you a positive experience. 🌹

Jump to this post

@dooshie my belly got puffy but I didn't perceive it as fat so that idea is interesting. Mine is back to normal. I have no idea when that happened.

Of course spinal fractures make my tummy stick out a lot more than Tymlos did, and there just isn't much room in there anymore.

REPLY
1 reply
esb13 | @esb13 | Sep 8 10:28am
In reply to @windyshores "When you first prime it, flick the pen with your index finger to get air bubbles..." + (show)
@windyshores

When you first prime it, flick the pen with your index finger to get air bubbles up to the top. Then do a full dose into the air to release the air bubbles. Air bubbles of course affect dosing.

My kid has type 1 diabetes and air bubbles have a serious impact on insulin delivery and can result in very high blood sugars, whether in a syringe, pen or pump line. I have gotten pretty good at flicking them up to the top!

@esb13 I am curious how air bubbles made their way into your Tymlos pen mid-month. I am not clear on how this is possible but if it is, it could be a concern for a lot of users.

Jump to this post

Exactly! Which is why I called. I do prime the pens before the first use so it was concerning that there was a very large bubble and more small ones that appeared mid pen and wouldn’t go away with tapping. It looked like a swag pen you’d get at a convention the bubble was so large. They did disappear after releasing the dose into the air, twice. I check now carefully before every injection for bubbles. I should add, the pen was in the same place and no travel or temp change or any external causation. Radius rep didn’t seem as concerned as I was and I was comforted that I have 6 extra doses incase bubbles appear again - which they did another time.

REPLY
1 reply
windyshores | @windyshores | Sep 8 10:44am
In reply to @esb13 "Exactly! Which is why I called. I do prime the pens before the first use so..." + (show)
@esb13

Exactly! Which is why I called. I do prime the pens before the first use so it was concerning that there was a very large bubble and more small ones that appeared mid pen and wouldn’t go away with tapping. It looked like a swag pen you’d get at a convention the bubble was so large. They did disappear after releasing the dose into the air, twice. I check now carefully before every injection for bubbles. I should add, the pen was in the same place and no travel or temp change or any external causation. Radius rep didn’t seem as concerned as I was and I was comforted that I have 6 extra doses incase bubbles appear again - which they did another time.

Jump to this post

@esb13 this is potentially very helpful to many!

REPLY
1 reply
esb13 | @esb13 | Sep 8 10:53am
In reply to @windyshores "@esb13 this is potentially very helpful to many!" + (show)
@windyshores

@esb13 this is potentially very helpful to many!

Jump to this post

I suspected it was a bad pen and Tymlos wouldn’t replace it for me. I have wondered if my poor P1NP increase after 3 months (yes, I am still obsessing about this) was because pen#2 was ineffective and I only had 60 legit doses not 90.
Good reminder to everyone to check for bubbles every injection.

REPLY
1 reply
dooshie | @dooshie | Sep 8 1:42pm
In reply to @esb13 "I suspected it was a bad pen and Tymlos wouldn’t replace it for me. I have..." + (show)
@esb13

I suspected it was a bad pen and Tymlos wouldn’t replace it for me. I have wondered if my poor P1NP increase after 3 months (yes, I am still obsessing about this) was because pen#2 was ineffective and I only had 60 legit doses not 90.
Good reminder to everyone to check for bubbles every injection.

Jump to this post

Over the 2-year period of Tymlos injections, I occasionally would get bubbles in the pen even after priming it. Sometimes not until a week later, would more appear. Like @windyshores, I would just flick the pen with my finger, sometimes they would just settle at the bottom, sometimes float around, but I injected regardless. Don’t know why they appear after priming, but they do.

REPLY
dooshie | @dooshie | Sep 8 1:46pm
In reply to @windyshores "@dooshie my belly got puffy but I didn't perceive it as fat so that idea is..." + (show)
@windyshores

@dooshie my belly got puffy but I didn't perceive it as fat so that idea is interesting. Mine is back to normal. I have no idea when that happened.

Of course spinal fractures make my tummy stick out a lot more than Tymlos did, and there just isn't much room in there anymore.

Jump to this post

@windyshores…I’ve always had a bit of a belly. I’m small framed and weigh 120 but Tymlos contributed to more belly fat and weight on my hips. It’s not puffy, it’s fat. Some of my pants are tight but my eating habits had changed for a bit even though I’m very active. I’ll blame it on my age too…72 and takes longer to drop weight. 😂

REPLY
1 reply
windyshores | @windyshores | Sep 8 7:35pm
In reply to @dooshie "@windyshores…I’ve always had a bit of a belly. I’m small framed and weigh 120 but Tymlos..." + (show)
@dooshie

@windyshores…I’ve always had a bit of a belly. I’m small framed and weigh 120 but Tymlos contributed to more belly fat and weight on my hips. It’s not puffy, it’s fat. Some of my pants are tight but my eating habits had changed for a bit even though I’m very active. I’ll blame it on my age too…72 and takes longer to drop weight. 😂

Jump to this post

I am about the same age @dooshie and I hear ya!

REPLY
trixi | @trixi | Sep 16 10:58am

Hi everyone, I am on my 2nd pen of Tylmos, and have been experiencing a painful hip, as well as ankles & wrists. I was expecting the ankles & wrists to be sore but am surprised with the hip. Is the hip pain also a side effect of the medication? I sure am thankful for this support group!
Thanks, Trixi

REPLY
njx58 | @njx58 | Sep 17 6:42am

A new pen has well over 30 doses. I'm guessing 35. I use a full dose, ten-second injection to make sure it all goes in, and there is always a decent amount in the pen left over after 30 days.

REPLY
1 reply
healthmatters | @healthmatters | Sep 17 10:36am
In reply to @njx58 "A new pen has well over 30 doses. I'm guessing 35. I use a full dose,..." + (show)
@njx58

A new pen has well over 30 doses. I'm guessing 35. I use a full dose, ten-second injection to make sure it all goes in, and there is always a decent amount in the pen left over after 30 days.

Jump to this post

Thank you 🙂

REPLY
View MoreView Less
Please sign in or register to post a reply.