12ish years ago, I had a C-Diff infection…a few years before a ruptured appendix. Both took 6 to 8 weeks to recover. Since then, my immune system has been in overdrive. After several years with lots of symptoms, I came across a FB page on Mast Cell Activation Syndrome.
Here is a bit of info, much more on the website…
https://www.webmd.com/allergies/what-is-mast-cell-activation-syndrome
What Is Mast Cell Activation Syndrome?
Mast cell activation syndrome, also called MCAS or mast cell activation disorder, is a condition that causes mast cells to release high amounts of chemicals into your body. This chemical release causes you to have many symptoms.
Mast cells are blood cells that are part of your immune system. They help you fight infections but are also involved in allergic reactions. Mast cells live longer than normal cells, growing in your bone marrow, gastrointestinal tract, skin, and airways.
When you come into contact with an allergen or substance that causes allergies, mast cells release chemicals called mediators that cause your body’s reaction to the substance. Some chemicals are released right away, and some take longer.
In a healthy person, these chemicals help protect and heal. In someone with mast cell activation syndrome, they cause distressing symptoms.
Sometimes mast cells can be activated or triggered by things like:
• Infections
• Medications
• Insect venom
• Reptile venom
• Fragrances
• Stress
• Exercise
• Food
People who have mast cell activation syndrome might have a lot of allergy symptoms and lots of episodes of anaphylaxis without a clear cause
During my medical workup, I discovered that I have the gene mutation called MTHFR.(very common)
https://www.medicinenet.com/what_does_the_mthfr_gene_mutation_cause/article.htm
I have trouble tolerating vitamins and no longer take multivitamins…my PCP has tested my vitamin levels and recommended specific types of vitamins to address deficiencies.