Connect
← Return to Is progress being made in understanding PMR/GCA?
Discussion
Is progress being made in understanding PMR/GCA?
Polymyalgia Rheumatica (PMR) | Last Active: Sep 22 2:50am | Replies (22)Comment receiving replies
There are some good papers on the pathology, treatment, and biomarkers, and these can be extremely helpful. The question of what triggers PMR is apparently unanswered.
The same author of the paper @dadcue found also has another paper on the pathology of PMR, published in 2020
https://www.sciencedirect.com/science/article/abs/pii/S1568997220302457
There is a good summary of the research as of 2022 for Giant Cell Arteritis at this link:
https://www.mdpi.com/2077-0383/11/10/2905
A video presentation of the same material is here, albeit with a heavy French accent
This 2nd group of materials are from a group in Dijon, France that apparently focuses on these subjects.
Replies to "There are some good papers on the pathology, treatment, and biomarkers, and these can be extremely..."
Connect
It really is an exciting "new age" in PMR/GCA research. Five years ago, my rheumatolgist wasn't overly confident about Actemra but said it may be my best chance of ever getting off prednisone.
I remember when I posted a question on another forum about treating PMR with Actemra. The forum itself with people who shared their personal experiences was great. The self proclaimed "experts" on the forum said my rheumatologist wasn't very intelligent and lacked some basic understanding that Prednisone was the "only option." Then the experts made sure I was booted off that forum because Actemra wasn't pertinent to them after I reported Actemra was working for me.
I still wish to know if and when I will ever get off Actemra. My rheumatologist is doubtful because of how the immune system is able to remember what it attacks chronically. The immune system memory is detrimental when a person has an autoimmune condition.