Good morning. I am 3.5 years in and yes the bone and joint issues have been awful. They wax and wane. I have blood abnormalities that show dysfunction in the megakaryocytes. Please look up studies related to this. I still need a walker for medium distance and a wheelchair for Long distance. Lots of weakness. For the pain I have started PEA. It takes a few weeks to start working on the nerve pain but it helps a bit. Some folks are getting osteoporosis but I have not been tested. Getting good medical care is still elusive and LC clinics don't have it together yet. I hope you get it figured out. Maybe you can access a dexascan to check your bone density?