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Methotrexate and Hydroxychloroquine

Autoimmune Diseases | Last Active: Oct 14 7:42pm | Replies (80)

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@jessmarin

Hi! I have been diagnosed with Mixed Connective Tissues Desease 3 months ago and my doctor prescribed me first Hydroxicloroquine and later Methotrexate but I am still have pain!! I am not sure it is normal!? . I have pain in my joints and muscles from my legs and arms. It seems medication haven’t made any improvements because I have a lot of pain! It is gonna be 4 months now taking these medication and feeling the same like before! Some days more pain than others

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Replies to "Hi! I have been diagnosed with Mixed Connective Tissues Desease 3 months ago and my doctor..."

It sounds to me like PMR. (Polymyalgia Rheumatica).have your CRP level checked by rheumatologist. I have had it and it caused havoc with me for months. I’m having a relapse now and back on prednisone. It is the only thing that takes away the pain.

Yes I agree, you may have been Misdiagnosed? Could be PMR Polymyalgia Rheumatica, see if you can get another opinion.
Prednisone is the only thing that helps the pain if it’s PMR
Good luck!!

I had swollen hands and ankles. Almost 2 years ago. My dr. Put me on prednisone. All swelling went away almost immediately. My pain went away too. Methetrixate and plaquenil was slowly added to the mix and I was weaned off prednisone. I have to continue on plaquenil and Methetrixate indefinitely unless my kidneys and liver are compromised. I have blood work once a month and check my eyes every 6 months. I am super healthy now and pain free and my body is not swelling. My RA seems non existent. I eat well. No meat and take nutrafol for my hair. I use elyptical 30 minutes a day and stretch my body when I wake up in morning. So far I am doing well and I will continue on my regiment. If you are still in pain have your doctor try something new. Good luck.