1. < Prostate Cancer

Anyone on Pluvicto (Lu 177), a new drug for prostate cancer?

Posted by dedehans @dedehans, Aug 20, 2022

My close friend has had Pluvecto treatment suggested to him by oncologists. It is relatively new, having been approved by the FDA in March 2022. Have any of you been given this drug? I have read it is radioactive material and patient needs to stay away 6 ft from others for at least 3 days so as not to contaminate them. He has not yet decided whether to take the treatment or not as he is feeling awful enough as is.

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lag | @lag | Sep 12 8:34am
In reply to @round5 "PSMA Scan Impression from yesterday after completing all 6 doses of Pluvicto in April: Reduced metastatic..." + (show)
@round5

PSMA Scan Impression from yesterday after completing all 6 doses of Pluvicto in April:

Reduced metastatic disease uptake with probable persistent low-level disease in a left lower neck node and left axillary lymph node. miPSMA Expression Score: 2

It might also be noted that I received 6 doses of Docetaxel and Carboplatin chemotherapy right before the Pluvicto. I completed everything in a 1 year period. I am still on Leuprolide and Darolutamide and my PSA is undetectable.

Appointment with Dr.Kwon this morning.

Jump to this post

Glad you can ask Dr. Kwon about the scan results from yesterday. Good luck and keep us posted.

REPLY
melcanada | @melcanada | Sep 12 8:44am
In reply to @round5 "PSMA Scan Impression from yesterday after completing all 6 doses of Pluvicto in April: Reduced metastatic..." + (show)
@round5

PSMA Scan Impression from yesterday after completing all 6 doses of Pluvicto in April:

Reduced metastatic disease uptake with probable persistent low-level disease in a left lower neck node and left axillary lymph node. miPSMA Expression Score: 2

It might also be noted that I received 6 doses of Docetaxel and Carboplatin chemotherapy right before the Pluvicto. I completed everything in a 1 year period. I am still on Leuprolide and Darolutamide and my PSA is undetectable.

Appointment with Dr.Kwon this morning.

Jump to this post

Starting chemo Doc wont let me go on daralutimide as Xtandi failed after a year

what does Leuprolide do is it zolodex

REPLY
round5 | @round5 | Sep 12 11:40am
In reply to @round5 "PSMA Scan Impression from yesterday after completing all 6 doses of Pluvicto in April: Reduced metastatic..." + (show)
@round5

PSMA Scan Impression from yesterday after completing all 6 doses of Pluvicto in April:

Reduced metastatic disease uptake with probable persistent low-level disease in a left lower neck node and left axillary lymph node. miPSMA Expression Score: 2

It might also be noted that I received 6 doses of Docetaxel and Carboplatin chemotherapy right before the Pluvicto. I completed everything in a 1 year period. I am still on Leuprolide and Darolutamide and my PSA is undetectable.

Appointment with Dr.Kwon this morning.

Jump to this post

Dr.said this was a good scan. Hoping the areas still showing are dead cancer cells. Will continue on Leuprolide and Darolutamide and repeat scans in 3 months. When the before and after scans were pulled up side by side in the office today there was a very significant difference. Difficult to find the spots they charted but previous scan was easy to see.

REPLY
1 reply
lag | @lag | Sep 12 12:44pm
In reply to @round5 "Dr.said this was a good scan. Hoping the areas still showing are dead cancer cells. Will..." + (show)
@round5

Dr.said this was a good scan. Hoping the areas still showing are dead cancer cells. Will continue on Leuprolide and Darolutamide and repeat scans in 3 months. When the before and after scans were pulled up side by side in the office today there was a very significant difference. Difficult to find the spots they charted but previous scan was easy to see.

Jump to this post

Very encouraging interpretation--good for you!

REPLY
melcanada | @melcanada | Sep 13 7:31am
In reply to @round5 "PSMA Scan Impression from yesterday after completing all 6 doses of Pluvicto in April: Reduced metastatic..." + (show)
@round5

PSMA Scan Impression from yesterday after completing all 6 doses of Pluvicto in April:

Reduced metastatic disease uptake with probable persistent low-level disease in a left lower neck node and left axillary lymph node. miPSMA Expression Score: 2

It might also be noted that I received 6 doses of Docetaxel and Carboplatin chemotherapy right before the Pluvicto. I completed everything in a 1 year period. I am still on Leuprolide and Darolutamide and my PSA is undetectable.

Appointment with Dr.Kwon this morning.

Jump to this post

Did you do 6 of doce and 6 of Carb

REPLY
1 reply
round5 | @round5 | Sep 13 7:54am
In reply to @melcanada "Did you do 6 of doce and 6 of Carb" + (show)
@melcanada

Did you do 6 of doce and 6 of Carb

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Yes

REPLY
melcanada | @melcanada | Sep 13 8:09am

Did Doce not get PSA down With Carb how low is it now

REPLY
1 reply
round5 | @round5 | Sep 14 7:33am
In reply to @melcanada "Did Doce not get PSA down With Carb how low is it now" + (show)
@melcanada

Did Doce not get PSA down With Carb how low is it now

Jump to this post

My PSA is undetectable just with Leuprolide however, I have a probable neural endocrine differentiation. Not all Prostate Cancer Emits PSA. The scans are definitive over the PSA. After my DociTaxel and carboplatin I still had some small Metastatic spots so we hammered it with the Pluvicto.

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