I was diagnosed in 2010 Gleason 3+4. Had surgery and they found it to be a 4+3. 3 1/2 years later my PSA started rising, so I had radiation. 2 1/2 years later, I came back again and I started on Lupron. 2 1/2 years later, my PSA started rising, so I was put on Biclutamide. One year later, my PSA started rising and I was put on Zytiga. 2 1/2 years later after a third and serious Afib event my oncologist told me off of Zytiga and put me on Darolutamide. A few months later, I had my one metastasis zapped with SBRT and my PSA has stayrd below .1 for the last 10 months. Just a matter of time before Darolutamide fails and then I can start a PARP inhibitor since I found out I am BRCA2 two years ago and that’s why it keeps coming back.

Now on Orgovyx instead of Lupron, 7+ years with ADT which is so feared by many, not a real problem.

14.5 years now and I really have no side effects from all the drugs, other than some hot flashes and a little brain fog.