After completing nearly six months on Orgovyx, I am pleased to report that it has effectively fulfilled its purpose. Beginning the medication just prior to external beam radiation with calypso markers, I experienced a significant decrease in my bio reoccurrence levels within the first month < .01. However, it is important to note that while the drug has been effective, it does come with its downsides. The persistent hot flashes 24/7 have been particularly troublesome, disrupting my sleep and resulting in occasional chills. Additionally, I have noticed a lack of drive, muscle loss, and a complete absence of libido. Despite these side effects, I believe that enduring them is well worth the benefits provided by Orgovyx. Furthermore, I have been informed that recovery from this treatment is relatively swift compared to other ADT therapies - which is certainly a significant advantage. Wishing you all the best and hoping this information proves helpful for you as well.