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Evenity and Bone Markers

Osteoporosis & Bone Health | Last Active: Oct 6 2:20pm | Replies (24)

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@windyshores

@marymj7 I had bone markers twice trying to catch bone growth, without success. P1NP may go up the first week or two. I got tested at the end of the first month and no change in P1NP, nor was there change in the middle of the third month. I have no idea what that means but doctor thinks I missed the best time to test: probably at the end of the 2nd week.

Your P1NP is lower than mine (my baseline is in the 50's and every test, whether at 18 months with Tymlos or with Evenity, it remains there). Would love to know what you get now. Evenity may be mostly anti-resorptive at this point, according to my doc.

I have not found bone markers to be helpful but it is all in the timing.

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Replies to "@marymj7 I had bone markers twice trying to catch bone growth, without success. P1NP may go..."

@windyshores Thanks so much for your response. I'm afraid the dexa scan is my only way to see if it worked after going through all 12 shots. Even that is dicey, as my last Dexa one year ago was done 3 months after a moderate L4 fracture, thus throwing off the numbers. I have had unexpected dental issues crop up-so I would definitely get off Evenity if it's not working. I didn't know that the anti resorptive phase kicked in so quickly. I know once I follow with a bisphosphonate I can't have extractions, which is scary. I had to get off of Tymlos due to hypercalciuria, which I still have at baseline, to a less extent than when on Tymlos.