I live alone too. I can't imagine a serious reaction in the sense of being dangerous (and I have occasional afib). To deliver a lesser dose you just do fewer clicks on the pen. When you rotate it to deliver a dose it clicks. Full dose is 8 clicks. It isn't going to hurt you to do a lower dose but it might hurt you to wait too long to take it (I don't know your bone situation).

People do lower doses of all kinds of medications to try them out. I often take 1/4 of a pill for instance (as long as it isn't time release).

Windy is right on the money with this one. I also live alone and plunged in at the full .80 dose right from the get-go and had some heart palpitations and BP drop that scared me. Windy had suggested the lower dose to start allowing my body to acclimate if you will. I told my Rheumatologist this is what I would do making certain I could tolerate the medication. I am finishing up my first month and have gone from .20 to .60. Very manageable. Living alone the fear of falling and NOT doing anything to improve bone health out weighed living alone and managing the side effects of Tymlos. Go slow and let us know how you do!

I live alone. Whenever I am given a new prescription, of a new type of medication, I do not take it until I have someone with me. One time I waited a week until I was at an appointment at a doctor's office and told them I had just taken the first dose. I might add, that people can get allergic to medications that have been safe taking in the past. Both Sulfa drugs and Ibuprofen started giving me hives after taking them for years.