Respectfully, let me clarify:

For the record, I confused Nanoknife (which uses electroporation to kill cancer cells using electricity) with Cycberknife which, according to their website delivers, targeted highly focused radiation. As I understand it both can be used for focal treatment of prostate cancer.

When radiation is used as the primary treatment for PCa the PSA drops until it hits its lowest post, referred in clinical terms as a nadir. It is not uncommon for the PSA to rise temporarily 18-24 after treatment. This is called a “bounce”. If treatment is successful the PSA hits a new nadir. Many professionals in the medical community consider that treatment has failed if PSA rises 2 points above the nadir or on consecutive tests.

Speaking not as a doctor but as an engineer that worked on medical devices I see potential for cure in some prostate cancer patients. I considered it in 2020 when I was originally diagnosed and my insurance wouldn’t cover the procedure. As with any other treatment, careful monitoring of PSA post treatment is critical to detect Biochemical Recurrence before it becomes a serious issue.

I received focal treatment in the form of low dose brachytherapy. My peak PSA was about 7.0 prior to treatment. I was sold on the premise that I’d be cured without risking incontinance or ED. The doctor had no established post treatment guidelines for PSA levels. As a result I was blindsided when after a steady then rapid rise is PSA I was diagnosed with Stage 4 Gleason 9 PCa. I hope that patients receiving treatment with Nanoknife have a care team that avoids the same as I had.

Here’s a link to reasonably recent published study on Nanoknife: https://www.mdpi.com/2072-6694/16/12/2178

Good luck to you on your journey.