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On Forteo 18 months - high CTX?

Osteoporosis & Bone Health | Last Active: Sep 20 9:49am | Replies (12)

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@gently

@midwestgirl
I've been waiting for someone wise to answer your question, so I could read it.
Because higher numbers represent more bone remodeling, it might be best when both CTX and P1Np are high. The tricky part is the ratio.
Decades ago there weren't medications that increased P1NP. Osteoporosis medications could only moderate the bone breaking down. So lower CTX was considered better.
But you need the bone to be broken down where it is weak so it can be replaced by stronger, unfissured bone. As CTX represents that clearing of older bone and P1NP represents the laying down of strong bone, I want high numbers of both working on my poor bones.
While I recommend questioning all of my suppositions, I offer one of my favorite videos which doesn't prove any point. https://www.youtube.com/watch?v=Cd0YT-OV97c

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Replies to "@midwestgirl I've been waiting for someone wise to answer your question, so I could read it...."

The video you reference is excellent. For me, it was my 'aha' moment about understanding bone remodeling and the complimentary/interdependent roles of osteoclasts and osteoblasts.
Highly recommended.