I am afraid of trying Tymlos and other drugs due to side effects

@sudsie58 my bone marker testing showed that Tymlos had stopped working at 18 months. Some of us are wondering if we can do more anabolic treatment after "locking in" gains so far with a bisphosphonate. Some posters have said that taking a break from Forteo or Tymlos will result in the medication working again. I plan on asking my endocrinologist about this next time.

These meds do improve bone quality and it is always possible that that effect continues past 18 months.

If your bone density has never been worse than -2.8 you have been in better shape than some of us! Did you get insurance approval for Forteo because of your surgery needs?

The horrible side effects means it has something to work on in your body. It means your immune system is ramping up and effectively doing something that is why I didn’t jump ship and when I was offered the other medication‘s, I looked them up and they weren’t as good so I decided to suck it up and Stay on the TMLOS. You are lumping all the medication‘s into one box. Maybe that’s all you have time for, but it would be better. If you lucked up all the medicines individually most people do not realize how different they actually are my dentist. lumped lump TYMLOS with the biphosphonates. And it is not! I hope you will stick with the TYMLOS until you get rid of the headaches. They go away. You can titrate up meaning start at two clicks and work your way up to eight it’s gentler that way some people stay on a partial dose the whole time, the medicine I am on the TYMLOS is only for two years and then I do a Reclast infusion once a year for three years and then I’m done for life. I went into menopause early at 47. I was on bio identical hormones for 10 years. I might start up again. I’m looking for a hormone specialist because my endocrinologist won’t deal with it I think your idea to use the HRT is a good one! I think you should work with the doctor or a specialist to get the testing all of it – the DEXA, the PNP, the CXT and monitor your bone density as you age. The side effects go away for most of us after two months you know what they say - no pain no gain. my life changed when the surgeon opened up my neck and the bones were paper. Thin and C5 fell apart. It meant they couldn’t do the cervical spine surgery as we had all hoped. I had done all the testing, but there are things which can’t be determined and you just gotta deal with it when it shows up, the bones in my forearm are strong and show no weakness. However, the bones that are in my neck aren’t worth shit. The bones in my lumbar were just fine when they did the surgery six years ago, so you never know. I’d rather be safe than sorry. That is why I’m putting up with the medication , I read all the reports and the reports now confirm all the testing that was done in 2017. There’s a lot of information here. I hope you get to it because many of us have asked these questions before and they’ve been answered by other members and there’s great information here. Good luck .

Hi I don’t know if this is where I type my concerns about Reclast, but I had a Reclast infusion 2 weeks ago and am still dealing with side effects. When one stops, another starts. I’m so fearful of repeating Reclast in a year. I’ve had bone pain, headaches, chills, aches, swelling in arm and hand which went away and am now dealing with eye aching and headaches again. My energy level was horrible for 2 weeks, but it is improving a little. I don’t think I’ve ever felt this sick before. Prolia didn’t help me so my Dr recommended Reclast. I am so afraid of aging and breaking bones easily with my osteoporosis, but I feel like Reclast is like a poison at this point. Can anyone offer advice or experiences with Reclast? I was told the side effects would last for 3-5 days. This has not been my experience. Thank you.

honestly - give it some time. It sounds like its working for you! There are tests to ask your doctor about P1NP, CTX, bone imaging and DEXA scans. If you see the numbers going in your favor you might feel better about ingesting the "poison." (it does feel that way, right?!) I have been on other really HORRID medications but my first Reclast was unbelievably bad. you are having bone aches because the medicine IS stimulating your system to do what the medicine is for. Don't give up. I was promised it wouldn't be bad when I go next time. The research does substantiate that! (I read it) but they put me on the Tymlos so I get a break for 3 years before I get another Reclast. Its the Cadillac of the bone meds so get the support you need to stay the distance! Talk with your doctor's endocrinology team if they have one. Call the pharmaceutical company too. Six months after I did the reclast I had an xray of my spine. Six months after that I had another xray. My surgeon could SEE my bones were denser!!! Hopeful, for sure! Good luck.

I’m on for a week now and moved to half dose since my nausea and headache is so bad. Should I stick it out?

I’m on for a week now and moved to half dose since my nausea and headache is so bad. Should I stick it out?

Hi I don’t know if this is where I type my concerns about Reclast, but I had a Reclast infusion 2 weeks ago and am still dealing with side effects. When one stops, another starts. I’m so fearful of repeating Reclast in a year. I’ve had bone pain, headaches, chills, aches, swelling in arm and hand which went away and am now dealing with eye aching and headaches again. My energy level was horrible for 2 weeks, but it is improving a little. I don’t think I’ve ever felt this sick before. Prolia didn’t help me so my Dr recommended Reclast. I am so afraid of aging and breaking bones easily with my osteoporosis, but I feel like Reclast is like a poison at this point. Can anyone offer advice or experiences with Reclast? I was told the side effects would last for 3-5 days. This has not been my experience. Thank you.

This sounds very difficult and discouraging for you. It is somewhat reassuring to read loriesco's reply and I hope these awful side effects diminish soon.
I am scheduled to have my first Reclast infusion this month and I am really hesitant and anxious. I've tried for many years to avoid this but my most recent scan scores clearly show that I need an intervention. Due to a blood protein issue, I can't use the anabolics, which I was hoping for as many of the comments reflect the benefits of managing the dose, unlike the Reclast infusions.
I hope to hear that you feel better soon.