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Strontium citrate (Algaecal) and fractures
Osteoporosis & Bone Health | Last Active: Sep 10 8:37pm | Replies (61)Comment receiving replies
This paper tells you all about strontium ranelate and includes that it should NOT be taken with osteoporosis medications such as bisphosphonates, e.g. alendronate (Alendro, Fosamax, Fosamax Plus), risedronate (Actonel, Actonel CombiActonel Combi D) and zolendronate (Aclasta); or denosumab (Prolia), raloxifene (Evista) or teriparatide (Forteo). Source: https://drlisacarroll.com.au/wp-content/uploads/2018/08/strontium_2016.pdf
This video makes a comment about strontium ranelate versus strontium citrate:
Go to minute 16:30 on this video https://www.youtube.com/watch?v=L9gw8wB5Loo
A study comparing three strontium formulations and their effect on bone density:
The three types of strontium salts studied are, strontium ranelate (SrR), strontium citrate (SrC), and strontium chloride (SrCl)
The administration of strontium salts led to a significant increase in trabecular and cortical tissue mineral density (TMD) in all experimental groups.
Among the studies, the SrC (strontium citrate) group exhibited the smallest increase in TMD.
These results may indicate that the administration of strontium significantly increases the mineral density of bone tissue, which is independent of bone mass, as it is converted into surface area.
Although some other studies have shown that Sr is more strongly incorporated into the trabecular bone compared to cortical bone, in our study, TMD increased similarly in both the cortical and trabecular bones.
Specifically, in the trabeculae, TMD increased by 36.9%, 16.5%, and 44.0% in the SrR, SrC, SrCl groups, respectively.
In the case of compact bones, TMD increased by 35.6%, 22.6%, and 40.0%, respectively.
These results are consistent with the findings of other researchers.
Our results revealed a positive correlation between the content of strontium in bone and TMD in both trabecular and cortical tissue.
Additionally, a positive correlation was observed in old (not producing hormones anymore) hens supplemented with strontium for 11 months for bone mineral density and bone mineral content.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11012416/
Here is another source https://blog.algaecal.com/strontium-ranelate-vs-strontium-citrate/
Replies to "This paper tells you all about strontium ranelate and includes that it should NOT be taken..."
I wouldn't assign much weight to Dr Lucas. He's quite a salesman. He posts a direct link to algaecal in this video so his promotion of this product is in his self interest. We clearly need more info on strontium from non-biased sources to determine absolute risk and benefit.
@healthmatters That looks like a very technical study that would take me a lot of work to understand. That's not a criticism, just saying. I do not see in your comment that it is a small mouse study (small in number of mice - not that they chose tiny mice). It's definitely something to keep in mind when talking about increases in TMD (which btw is a term I am unfamiliar with).
When most human studies are talking about percentage increases in bone density they are talking about DXA scans in humans. That's how Evenity, Forteo etc are being evaluated. These percentages are in Ovariectomized mice using micro ct. Not saying this isn't good or important research, just saying it's important to remember that this is not apples to apples with the numbers commonly seen in this group when discussing increases in bone density.
Thanks for bringing this paper to our attention.
My cardiologist also advised against taking strontium due to my blood thinner.
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@health matters in his video Lucas mentions the oft repeated warning that strontium "falsely elevates" bone density on DEXA. He is the first I have read or seen to say that this elevation is real and may not be false. I have doubts about this and am going to look into it.
Strontium replaces calcium in bones and is heavier/denser than calcium. The DEXA therefore reads higher.