Whether biochemical recurrence prostate cancer returns after testosterone (T) levels starts to increase after finishing ADT treatment is a fair, reasonable and sometimes hard topic to review. My health team has indicated that with my confirmed BRCA2 gene mutation and the PSMA PET from October 2022 that had 25+ lymph nodes lit-up with a PSA of 19 before ADT treatment, that it is probable that the PSA may start to rise as the T rebounds, however the timing of such sequence of events is more of a mystery and less of a science.

In the world of self-education on the internet and the abundance of misinformation, I'm leaning into this next chapter with a mindset that healthy diet with exercise can be a differentiating factor. At the same time, if I had to resume ADT, I'd be so much more prepared as the side effects would not be brand new experiences and the multitude of coping mechanisms would be available rather than figuring it out.

hope this helps!