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Resolution of Side Effects after Stopping ADT/Lupron

Prostate Cancer | Last Active: Sep 7 12:13pm | Replies (25)

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@retireddoc

Kevin, enjoy your posts and obviously wish you the best. I have posted multiple times before but recap: 71 with G9 oligo, T8 solitary met on PSMA PET 4/22 treated with SBRT, rising PSA in 9/22 with repeat PSMA PET revealing +pelvic node but no T8 activity, triple therapy (Lupron, Darolutamide and Taxotere) at Hopkins completed 12/22. pelvic radiation 4/23 with 37 treatments, PSA undetectable since mid triple therapy (11/22), off Lupron with last 3 month injection 7/22/23. On no meds. My T pre treatment was around 450.

The SEs of the ADT have been difficult to handle- depression (on antidepressants), fatigue, joint/muscle stiffness, hot flashes (almost gone) and, to add insult to injury, genitalia shrinkage. My last T in June was 30. The docs at Hopkins say most men either start to recover or recover their T about 9-12 months after the ADT has worn off. I'm still hopeful but it has been difficult.

Your story is encouraging. Thanks for sharing.

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Replies to "Kevin, enjoy your posts and obviously wish you the best. I have posted multiple times before..."

The more important question is , when ADT side effects go away, will a rise in PSA occur soon? Let’s sing the song by Kenny Rodgers, The Gambler. Lol