I am on Xalkori and have been for 8 years. Had LLL 8 years ago and taken 200m tablet 2x a day for years. Have been on 1 200m pill for a year and so far CT scans "unremarkable". I am very fortunate. My biogenetic markers fell into perfect alignment for this treatment.
As for side effects....I cannot take the xalkori without zofran pill as I throw up without it. When I took 2 doses a day I would take before a meal ...breakfast and dinner...)

The swelling of my legs and ankles comes and goes.....have heart issues so have to address it....I have taken spironolactone to reduce the swelling but it makes me feel awful so I try hopefully to reduce the swelling by drinking lots of water.