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Input on PSA rise 3 yrs Post RP

Prostate Cancer | Last Active: Sep 4 12:15pm | Replies (14)

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@azp52

I want to thank all of you immensely for your invaluable input. I have a PSMA-PET scheduled for Sept. 13. The question then is if nothing shows at that time, do we proceed with salvage radiation. Seems the majority opinion from doctors is to proceed with salvage radiation given PSA level has increased to >0.4 . Again, thank you!

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Replies to "I want to thank all of you immensely for your invaluable input. I have a PSMA-PET..."

The doctors are not "wrong" that SRT is a treatment choice based on an increasing PSA in the absence of imaging showing where the recurrence is.

Have they discussed:

Including the pelvic lymph nodes?

Adding ADT and an ARi for a defined period, that could be anywhere from six to 36 months though 18-24 seems to be the sweet spot.

Why would you include the PLNs in the radiation treatment plan...given your high risk clinical data, there is a distinct possibility the PCa has spread there.

The same for adding the ADT and ARI, to deal with micro-metastases or systemic cancer.

SRT as mono therapy is circa 2016 thinking, especially to the prostate bed only.

Discuss doublet and triple therapy with your medical team.

Kevin

Yes, you proceed and probably with ADT as well. My situation and scores are almost identical to yours. My PSA hit .18 Five yrs after surgery and I’ve been on ADT (Orgovyx) for one month today. Will be on that for 6 months total during which time I will have 25 radiation treatments. Both my MRI and PSMA were negative.
Catch it NOW before it catches you….this thing requires life long
Vigilance and it will surely pay off in the end. Best