Hi - by your question "is it safe to cancel", I assume you are asking Will cancer progress without chemo. That's really a question for your oncologist, but really depends on other information that you have not presented. For example has circulating tumor DNA been assessed? If you are in the US you can get Signatera covered under Medicare. Recent data presented at ASCO, indicates that a negative ctDNA result 30 days following surgery, suggest adjuvant therapy does not have a better outcome then going without chemo. Please ask your doctor about this. As I'm sure you're aware the age is also a significant factor to consider. At many institutions chemo would not be considered simply because of age. I know I would be thrilled just to have 82 years under my belt