My husband also has cancer at the GE Junction. When he was first diagnosed they were unable to complete the endoscopy because the tumor blocked the passage. After 28 rounds of radiation and 6 weeks of chemo the tumor had shrunk. He started a new regimen of FOLFOX, Keytruda, and Herceptin and the tumor shrank even more. Recently he had a UTI that led to sespsis and he started passing blood; he was throwing up, it was in his tube, and in his stools. After GI doctor performed a GED they were able to spray the tumor and several ulcers that had developed as a result of the chemo. The bleeding stopped but we were told that this was only a temporary fix and that in the future he would likely continue to need blood transfusions on an outpatient basis .