The maximum dose I've taken over many years is 75mg, so there haven't been many changes for me to remember--just my two efforts to eliminate it. I have made notations on a calendar regarding those, so I can refer to that if needed. Frankly, the experience has been so distressing that it's hard to forget.
When I saw my gynecologist earlier this year (the one who prescribed Effexor died of Covid years ago), and told her about my ordeal trying to get off the drug, she said very casually that she still prescribes Effexor for hot flashes. After my chin hit the floor, she said, "Not everyone has the problem getting off of it that you do." I was too stunned to tell her that too many do! And with more people being on anti-anxiety drugs due to the pandemic, I suspect that we will be hearing more in the future from people who try unsuccessfully to discontinue the drug. Perhaps as our numbers become greater, the FDA and pharmaceutical companies will finally address the needs of those of us who are struggling to end this drug dependency.