TURP Alternatives

Posted by oldoz @oldoz, Aug 31 8:38pm

TURP alternatives question?
72 year old. Been on Tamsulosin and Finasteride for years, later on the Doctor added Myrbetriq which was like the magic pill relating to no more getting up multiple times a night. After a couple of years that gradually quit working at about the same time that I had my annual physical/wellness exam, and my doctor told me I was in excellent health, except my PSA which had been gradually climbing had shot up from 3.6 to 8.1 in one year. He sent me to a local Urologist that did multiple tests, then did a conventional biopsy giving me a (3+4)7 score 18 months ago. He had some other test (genomic???) that indicated it didn’t appear to be real aggressive. He recommended we do Active Surveillance. PSA tests have stayed high. He did decide to do a bone scan 6 months ago which didn’t reveal any likely spread. Last month he had an MRI done. He told me it showed a couple of hot spots (?). Then said I will need to at some point get Radiation or a Prostatectomy because it would likely spread in the next ten years. But, what he wants to do now is a TURP, because he said on my last three visits the Ultrasound showed I was unable to fully empty my bladder, which is why I’m back to getting up 3 times at night again. He said besides the loss of good sleep that I was injuring my bladder and he needed to do a TURP procedure at the local hospital. I asked about alternatives and he said there were some, but he does the TURP, and had one of his Assistants schedule it for next month. I looked to get a 2nd opinion but this being a fairly small town there are not a lot of advanced options.
I am now wondering if I just go to the Arizona Mayo Clinic and have the prostate removed and if that would solve both the bladder flow and prostate problems, without having to go through 2 recoveries? Apologize for the length. Appreciate any thoughts.

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@michaelcharles

Personally, I would seek a 2d opinion and focus on my PCa treatment.
Best wishes.

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Thanks - That's what I'm thinking also. I didn't ask my current Urologist all the necessary follow-up questions at my last appointment, such as how am I injuring my bladder by not being able to fully empty it. Is this simply a large prostate or some other obstruction. Going to move forward with another opinion and will bring a list of questions next time.

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@tuckerp

I had mine removed LARP with bladder flow issues prior. I still have those issues. I am also incontinent for the most part and lack erections. Those are new since the surgery. However, I am 5 years out from surgery. No other treatments. Zero PSA. I cant say whether the surgery would stop your prostate issues. I didnt wait for mine to get any worse.

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Thanks, I like the Zero PSA part.

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@bens1

@oldoz doctors have a natural bias towards doing procedures that they have had success with and are used to doing. They are dedicated but not infallible. You are clearly considering Mayo in Arizona which is great but being in a small town does not limit you from sending any blood work, imaging, biopsy report and any genomic testing, i.e. Decipher test, to a center of excellence and have a zoom consultation. It is done all the time.

I had a 3+4 Gleason with a PSA of 10.2. I did not want to wait for it to grow and potentially cause more severe treatment and side effect problems. I had 5 hypo-fractional treatments with the mridian linac radiation machine with has a built in mri so its all real time treatment. What the radiation oncologist sees is what they treat vs other forms of radiation machines that use fused images. Secondly, many of the radiation treatments involve treating the entire prostate PLUS extra space, called margins. The margins with the mridian were 2mm instead of 3-5 mm with other types of radiation machines. This meant potentially greater side effects. Google the Mirage randomized trial.

There are many choices that people have made successfully on this web site, including removal and partial removal, which is comforting to know. My decisions were made on my definition of cure, side effects and quality of life in the short, medium and long term. Good luck.

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How long do out of area people have to stay in town to get this done. I could motel it for a week or two, not if I have to come back once a week for months. Thanks for the explanation.

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Hi, oldoz. Your concern about TURP is understandable, but I hope my experience will ease your mind. I had prostate interference with urinating 15 years ago, and my urologist convinced me to endure a TURP. I'm glad I agreed. The procedure in the hospital caused no pain or regrets. In fact, removing the prostate instrusion of my bladder exposed a small tumor on the bladder lining; it was removed and diagnosed as moderately malignant. However, it was discovered at an early stage and had not grown roots deeper than the epithelial (lining) cells, so its removal was complete. To be sure, we scheduled another cystoscopy two weeks later, and that viewing showed several more small tumors on the bladder lining. Another TURP removed them and led to another diagnosis of malignancy, but again they were superficial in place, easily removed, and left no bad tissue behind. Still cautious, we turned next to what is known as a Bacillus Calmette-Guerin (BCG) treatment that injects a solution into the bladder in up to six weekly applications. The solution contains immune system cells designed to neutralize any seeds of malignancy without causing any significant discomfort or extended symptoms. Like you, I had been on medications that fell short of opening my urinary system to free flowing, but after the TURP and followup treatment, my problems were a greatly relieved, medications were stopped, urination remains dependable, my last cystoscopy (after 15 years) led to no further bladder treatments. I'm now proud to acknowledge being a cancer survivor. Martin

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@oldoz

Thanks - My biggest concern is getting rid of the cancer, and being able to urinate without having to but in a catheter every time I get the urge to go. I accept that I will have side effects, and I'm unfortunately already use to poor sleep.

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@oldoz -- Yeah, I agree. I'm actually very happy with my surgical outcome at Mayo Phoenix. Dr. Paul Andrews was my surgeon at Mayo and I think he did excellent work on me. That said, I agree with @jeffmarc's comment that your data is pretty old and you'll probably need some new tests to determine the most effective treatment for you. But Mayo Phoenix is a cancer center of excellence and I believe they'll give you excellent advice on additional testing and treatment options. As someone already mentioned, I'd also recommend getting Dr. Patrick Walsh's Guide to Surviving Prostate Cancer Paperback – October 3, 2023. It's on Amazon and it's the best $20 I ever spent. It really helped educate me on some key points in my decision making. Best wishes to you and yours.

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@jeffmarc

Waiting 18 months with a 3+4 may not have been advisable. There’s a good chance of spread. You should get another biopsy and see what’s going on, more likely the cancer has spread in your prostate and your Gleason score may be higher.

You definitely should be seeing a different doctor. Active Surveillance is more for 3+3 than 3+4. Get to the Mayo Clinic ASAP.

A prostatectomy would completely replace a TURP. You might be in a situation where you get the TURP and then need a prostatectomy, so all the pain and time wasted on the TURP is totally wasted.

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You just maid me go on high alert, I will call and request an appt ASAP. Thanks. I thought retiring to a area with a good size hospital was safe, didn't really understand that is primarily for traditional/standard care/and emergency room visits.

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@predictable

Hi, oldoz. Your concern about TURP is understandable, but I hope my experience will ease your mind. I had prostate interference with urinating 15 years ago, and my urologist convinced me to endure a TURP. I'm glad I agreed. The procedure in the hospital caused no pain or regrets. In fact, removing the prostate instrusion of my bladder exposed a small tumor on the bladder lining; it was removed and diagnosed as moderately malignant. However, it was discovered at an early stage and had not grown roots deeper than the epithelial (lining) cells, so its removal was complete. To be sure, we scheduled another cystoscopy two weeks later, and that viewing showed several more small tumors on the bladder lining. Another TURP removed them and led to another diagnosis of malignancy, but again they were superficial in place, easily removed, and left no bad tissue behind. Still cautious, we turned next to what is known as a Bacillus Calmette-Guerin (BCG) treatment that injects a solution into the bladder in up to six weekly applications. The solution contains immune system cells designed to neutralize any seeds of malignancy without causing any significant discomfort or extended symptoms. Like you, I had been on medications that fell short of opening my urinary system to free flowing, but after the TURP and followup treatment, my problems were a greatly relieved, medications were stopped, urination remains dependable, my last cystoscopy (after 15 years) led to no further bladder treatments. I'm now proud to acknowledge being a cancer survivor. Martin

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Thanks - Was your treatment at Mayo?
My Dad died a 83 from cancer of the bladder and kidney. He waited to long for treatment and as I understand it the radiation just slowed it down until it spread everywhere. I mentioned that to my urologist as a family history and he discounted it because dad was a smoker, and I wasn't.

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@oldoz

How long do out of area people have to stay in town to get this done. I could motel it for a week or two, not if I have to come back once a week for months. Thanks for the explanation.

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@oldoz my 5 treatments with the MRIdian were: Date Started: 01/31/2023 and the Date Completed: 02/14/2023. Twice per week.

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@grandpun

All good advice above. Especially using a Center of Excellence and your consideration of Mayo Phoenix would be well worth it IMneverHO.
I had the same Gleason score 3+4 at age 75 but with the caveat of the worst area being near the margin (possible escape of PC) so I went right for the RALP (done 1/2022). However, the pathology of the tumor sadly but in a very valuable way showed "positive" margins; the PC had escaped. To me, this clear info was the advantage of prostatectomy. I/we knew what the situation was and I did 2-years of ADT (Lupron). Now my PSA is negligible for which I'm most thankful.
You might strongly consider Dr Patrick Walsh's book, "Surviving Prostrate Cancer" (available at Amazon & etc). For sure get the latest edition as the older versions don't contain the extensive improvements in PC diagnoses and treatment of the last 5-years. It will also address your concerns of continence and frequency post treatment.
And don't forget the "active" part of Active Surveillance. I"m sure that term intends to encourage research such as: quiz multiple doctors/specialissts, read, study, computer search, and dig into all the info you can.
God Speed to you on this life changing and, most hopefully, reaffirming journey!

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Thanks for the info, I just ordered the book!

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I should mention that I also had a 3+4 after biopsy. I had surgery and it turned out I really had a 4+3. In the last week I have spoken to three other people that had the same thing happened to them 3+4 was really a 4+3. A biopsy does not check all of your prostate.

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