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3 month TYMLOS findings

Osteoporosis & Bone Health | Last Active: Sep 4 11:48am | Replies (12)
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@mayblin

Hi @esb13, @gently explained the possible reason for your bone markers' response really well. If I were in your shoes, I might want to have both p1np and ctx monitored every 3 months going forward if there are no problems with lab ordering or payment. The greatest increase in p1np during Tymlos' therapy tends to occur in early months for treatment-naive patients. Since you had prior reclast treatment, the increase in p1np may be delayed like @gently had explained, although it might be hard to predict the length of delay.

Before you started Tymlos, were you on a drug holiday from reclast? If so, for how long?

Best wishes!

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Replies to "Hi @esb13, @gently explained the possible reason for your bone markers' response really well. If I..."
esb13 | @esb13 | Aug 31 11:52am

Testing every 3 months sounds like a great plan. Last reclast infusion was a while ago - 2021. And my DEXA held steady during the holiday with no change in spine (t-3) and no OP in hips or Femoral neck. So I may be one of the unlucky ones re: TYMLOS but I will think positive and hope I improve slow and steady.
It's so very mentally taxing knowing I have OP but have no outward symptoms - I am not used to this level of health concerns and uncertainty about treatment and extent of possible disappointment after so much hype about TYMLOS and no sense of next steps if I do not improve.
Thank you so much @mayblin for your kind support and time to share your thoughts.

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