I have an undiagnosed autoimmune illness that causes pain. My GP thinks it's fibro, but the rheumies do not. In some ways, it behaves like that, but in other ways not. I get signficant pain, but it is months between and usually only lasts 24 hours, and has never been pinpointed in the ER or by any other tests. Just high ANA. All that to say, my dr originally put me on Dulox, and the pains increased, and I began having panic attacks, but over time they subdued. The only noticeable side effect I had was more sweating, a lot more. It did help with my general anxiety. The biggest problem I had was it made me crave wine, no kidding it's a thing. It got to a point where I was drinking too heavily and impacting my life negatively (which by the way is unsafe on Dulox due to enhanced effects on the liver), so I had to quit. I tapered down by taking out a few of the "balls" in each pill per day, and had zero side effects getting off (took a few months). Haven't touched wine since then (2020) and have no interest.

I went back to my doctor as the pains became more frequent and the anxiety went through the roof with routine panic attacks. I think I got used to being on the antidepressant. I am on gabapentin now, which helps with nerve pain and somewhat with anxiety. I still have higher anxiety than I would like in random situations (like getting an MRI, dental work, driving over a bridge, just random stuff that appeared out of nowhere after quitting dulox). But it's manageable. Anyway, that's a long way of saying maybe discuss gabapentin with your doctor. It might be an option.