@gently that post of mine with its recommendation to "make sure to test blood and urine" and have a Cystatin C reflects my own experience and should have been written in that context only. I have a lowish creatinine based eGFR but my Cystatin C is better and my nephrologist told me it is more stable.
My calcium level was tested in blood before starting Tymlos along with a bunch of other standard blood tests. My urine was not tested. In some threads, people write about how their blood test was okay but not their urine calcium, and I should have referred to those people. I did not have a urine test. My blood calcium as at the high end of normal at 10.3 but I had no problems.
My understanding from my doctor was that Tymlos can cause kidney stones but not kidney damage. It is best to check this with a doctor.
Any time I catch slippage into giving medical advice, in any serious way, I contact the administrators and ask them to delete it. The post cited is borderline. If I could I would rewrite it.
I have never heard of reducing Tymlos to protect the eGFR. My doctors tell me the creatinine based eGFR is quite complicated and can be affected by many things, including low blood pressure, muscle loss- and that is why they do the Cystatin C for me. Perhaps @ gently can provide a link. The idea that Tymlos can reduce the e GFR might be needlessly alarming . A doctor with training on this could clarify.
I looked for the link, what I found in addition were later studies indicating that a reduction in dose was not necessary.