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Tymos and kidney function?

Osteoporosis & Bone Health | Last Active: Aug 25 7:15pm | Replies (9)

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@gently

@anewyorker

windyshores | @windyshores | Feb 26 7:58am https://connect.mayoclinic.org/discussion/kidney-problems-while-taking-tymlos/
"Tymlos raises calcium levels for a few hours so make sure you test blood and urine before Tymlos.

It also lowers blood pressure for an hour or two which can affect testing for kidney filtration rates.

I would make sure to have a Cystatin C rather than a creatinine based GFR if you can: it is more stable."

There is an article somewhere about reducing the dose of Tymlos if it is affecting eGFR.

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Replies to "@anewyorker windyshores | @windyshores | Feb 26 7:58am https://connect.mayoclinic.org/discussion/kidney-problems-while-taking-tymlos/ "Tymlos raises calcium levels for a few..."

@gently that post of mine with its recommendation to "make sure to test blood and urine" and have a Cystatin C reflects my own experience and should have been written in that context only. I have a lowish creatinine based eGFR but my Cystatin C is better and my nephrologist told me it is more stable.

My calcium level was tested in blood before starting Tymlos along with a bunch of other standard blood tests. My urine was not tested. In some threads, people write about how their blood test was okay but not their urine calcium, and I should have referred to those people. I did not have a urine test. My blood calcium as at the high end of normal at 10.3 but I had no problems.

My understanding from my doctor was that Tymlos can cause kidney stones but not kidney damage. It is best to check this with a doctor.

Any time I catch slippage into giving medical advice, in any serious way, I contact the administrators and ask them to delete it. The post cited is borderline. If I could I would rewrite it.

I have never heard of reducing Tymlos to protect the eGFR. My doctors tell me the creatinine based eGFR is quite complicated and can be affected by many things, including low blood pressure, muscle loss- and that is why they do the Cystatin C for me. Perhaps @ gently can provide a link. The idea that Tymlos can reduce the e GFR might be needlessly alarming . A doctor with training on this could clarify.