My husband's cancer had spread from pancreas to lungs, bones along spine, and lymph nodes before he even knew he had cancer. They treated him first for lung cancer... said the spread wasn't "normal" for pancreatic cancer so that doctor (and also the second opinion at cleveland clinic) decided the primary was lung cancer. Bad choice as of course that chemo and immunotherapy did nothing. Delayed proper treatment for many months until we made the wise choice of a new oncologist. He's had nothing specifically targeting the mets in lungs... simply chemo targeting pancreatic cancer.