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High anxiety regarding Reclast or Prolia decison for OP meds
Osteoporosis & Bone Health | Last Active: Sep 22 4:39pm | Replies (165)Comment receiving replies
@awfultruth i think you made a good call. I will do the same if i need a big bmd boost to reduce frax risk. Trial results clearly showed there are further bmd increase during 7-12 months of evenity treatment, by a good margin. The numbers in bmd increase vary depending on which paper you are reading, but generally greater than 3% - a margin many studies deem as "significant". Unless, you have a way to relay to an antiresorptive then back to evenity and show more advantage over a straight 12mo treatment. So far no studies showed that yet.
Did you have your bone markers monitored during evenity treatment?
We had a discussion a few days ago re if it's oversimplified to say first few months are anabolic (btms are saying otherwise) and last half (maybe?) is antiresorptive during 12mo evenity treatment.
I will try to attach the actual graph of bmd changes for 24mo evenity later. The link was in an earlier reply.
Could you keep us posted re your dexa results at the completion of evenity? Thanks!
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@mayblin Thanks for your interest. I have a baseline and a two months marker tests. Doctor did not think any needed after the two months test results. Not sure if that's right but I didn't fight about that one.
At 2 months after my first shot my P1NP almost doubled and my CTX went down by 68%. So that little snippet of data looks good.
Started Evenity 10/16/23 (no prior meds)
CTX 9/22/23 763
CTX 12/18/23 268
P1NP 9/22/23 69
P1NP 12/18/23 130
Note that my previous bone markers were not as high as my baseline markers above. I mean 763 for CTX and 69 for P1NP are both high numbers when not taking any meds. Prior to that my CTX had been in the 200's and then jumped to 400's and then to that number above (763). My P1NP had previously varied between 33 and 50 usually around 40. Maybe I had a silent fracture in the months before starting Evenity? Maybe these two markers jump around like that without medications? My doctor did not comment on the increase in both markers except to say the increase after my Evenity shots was a good sign.