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High anxiety regarding Reclast or Prolia decison for OP meds
Osteoporosis & Bone Health | Last Active: Sep 22 4:39pm | Replies (165)Comment receiving replies
It's so confusing!
At this point in my decision journey, my research points in these directions. But surely, there are other options and sequencing protocols. But maybe not.
1) Evenity>>Prolia 1 yr. >>Reclast
2) Evenity>>Prolia 1 yr. >>Evenity. Dr's prescribed sequence
3) Evenity >>Reclast
Each option has pros and cons. I'd like to avoid the Prolia and the rebound effect after stopping, even after 1 year. I'm not convinced the dual actions of Evenity has enough ummp (!) to blunt the rebounding of Prolia. I understand the proposed jump in BMD we should get from the Prolia, but not everyone responds with great gains. So why take it?
Realizing my spine is _4.7, after Evenity, is Reclast not what I need?
Reclast adverse side effect bother me. Just how bad is it!
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@255anny I think you are doing great with your reasoning. As you know the problem is there are not enough studies asking the right questions for our reasoning to be foolproof. I'm agonizing over a similar situation myself.
My suggestion would be Evenity - Reclast - Evenity - Reclast. Basing your use of Reclast on bone markers (and DXA results), not on the "just doing a yearly dose method". As I said previously I see inserting Prolia into the mix bringing in a lot of uncertainty and worry for only a slightly increased bone gain.
There are certainly real risks with Reclast too but multiple fracturing is not one of them. I would consider the lower dose route with Reclast which would theoretically reduce the risk and impact of Reclast side effects. I'm probably going to be discussing (arguing?) about this with my doctor this week.
See my post on studies showing lower dosing with Reclast works well:
https://connect.mayoclinic.org/discussion/reclast-iv-half-dosage/?pg=2#comment-1127778