That's the amazing thing about organic chemistry. The hormones have a wide-ranging impact on the human body. I'm constantly surprised at my changes in thinking and processing information. Since adding progesterone back in April, I've noticed a very pleasant calming effect rather than the anxiety that would surface from time to time. Estrogen has clearly had an impact, resulting in an emotional and mental clarity that had escaped me all these years. Though the primary goal of the progesterone was enhanced breast development, the calming nature is a wonderful side benefit.