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High anxiety regarding Reclast or Prolia decison for OP meds
Osteoporosis & Bone Health | Last Active: Sep 22 4:39pm | Replies (165)Comment receiving replies
@255anny no problem. I think I'm making myself confused here 🙂
Then really it comes down to which antiresorptive as a relay in between the two rounds of evenity is better. That's the big question. You'd have a better picture if you could find evenity-->reclast-->evenity study. Then compare which relay drug attenuated evenity's effects less. Head to head studies are likely non existent. Your endo might know a lot info about the differences in results between the two.
Hypothetical questions to both you and @windyshores, can you just go straight for a 2nd year of evenity if can get prior authorization (an after thought: it seems 12-24mo bmd increase not that much if used continously for 2 yrs)? Why a full year antiresorptive? Can you do 1 shot of prolia (a lot safer) or 1/2 dose reclast, i.e., a 6mo antiresorptive then to 2nd round evenity?
Replies to "@255anny no problem. I think I'm making myself confused here :) Then really it comes down..."
Agree, if only there were more studies and more answers. These drug manufacturers make it so hard - maybe being a little cagey. You make some great points, why does every treat have to be a year?
I've wondered about 2 straight years of evenity. I've read so much and watched so many videos, it's a blur. But somewhere, I did that mentioned. And am I dreaming, but does Evenity lose most of it's efficacy after the first few months? And of course insurance might be an issue.
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@mayblin Reclast does decrease effectiveness of Evenity. I wish there were studies on low dose, one year, 6 months etc. and how much of a break is needed to maximize effectiveness of an anabolic or Evenity after Reclast, whether a first or second course of the anabolic.
My doctors aren't even discussing repeats of Evenity though at one point my doctor said he wanted to save Evenity in case it was needed later (after Tymlos and Reclast). I still have 8 months left of that first year!
I like the idea of "treat to target" but some of are just not going to get there and maintenance will be the main goal. Not sure when that will happen for me, personally. I want another shot at an anabolic or Evenity!
I would not do two consecutive years of any of the anabolics but Evenity's amabolic action seems to fade faster than that of Tymlos or Forteo. The potency of it for the remaining months is a mystery. Perhaps that quick large jump in P1NP takes a long time to mineralize. My doc says they don't know.