← Return to High anxiety regarding Reclast or Prolia decison for OP meds

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@windyshores

If you do Prolia for 1-3 shots, Keith McCormick, author of "Great Bones" has mentioned that the Prolia rebound will be more gentle and can be handled with Reclast or even Fosamax.

When Prolia is stopped, as you probably know, there is a "rebound" with drop in bone density and rise in fracture risk as the dormant osteocytes wake up. Other meds need a bisphosphonate to "lock in" gains but my doctor says it is especially important with Prolia (in fact my doctors rarely use Prolia due to rebound).

With -4.7 at the start, can you have a scan to see where you are now? Maybe your doctor intends one year Prolia, then Reclast then a repeat Evenity? Or Prolia, Reclast and Tymlos or Forteo?

We need more research! Evenity came on the market in 2019 and is so new. The company suggests Prolia after Evenity but generally the info I read and see says that after Prolia you have to do a bisphosphonate ("Great Bones," various videos on YouTube including Ben Leder's "Combining and Sequencing Approaches to Osteoporosis."

Leder says Prolia is quite potent to build bone density and the only issue is with stopping. I don't see how Evenity would stop rebound, but that is speculative and your doctor can discuss this with you. Maybe they have new info. Let us know!

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Replies to "If you do Prolia for 1-3 shots, Keith McCormick, author of "Great Bones" has mentioned that..."

I have Keith's book so I will check that out. Even with just 2 injections of Prolia, I've read there can be issues with the rebounding effects. I've watched OP conference presentations til I'm blue in the face. I've read so much. If I don't understand something, I Google it. Thanks for the YouTube suggestions - going there now.