@lhankins I only know from my kid's type 1 diabetes that tummy is the best site for fast absorption. I believe I saw a chart that included thighs for Tymlos but can't find it. I didn't have any problems doing it in my tummy. Studies were done with tummy so the company, pharmacy and doctor often stick with what was done in a study.

You can go down to 1/4 dose (two clicks) if you prefer and if that is absolulely fine, move up. Or you can try a half dose and see how that goes and go down to 1/4 if that 1/2 still gives problems.

I was literally in the ER with a full dose but dafter introducing my body to it slowly, did almost a full dose for almost two years and had huge gains. Good luck!

ps Doing it in the morning, I found that getting up and about helped my side effects, maybe because it raised my blood pressure. Play around with timing, hydration and rest vs activity.