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1.3 rise in yearly PSA and BRCA2 Positive

Prostate Cancer | Last Active: Aug 18 1:12pm | Replies (6)
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@cudabinacontenda

Jimmy, do you have a BRCA2 mutation of known “deleterious” consequence or one of “uncertain significance?” I’m currently being monitored for a PSA spike and have a BRCA2 mutation of uncertain significance. I’m 64 with a normal PSA of around 1.0. Two months ago, my test came in at 4.1. Six weeks later, it dropped to 2.59 without using antibiotics. The urologist is going to retest in three months and then make a decision on MRI. I have a history of chronic prostatitis and a 15-year annoying problem with urinary urgency but never an abnormal PSA

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Replies to "Jimmy, do you have a BRCA2 mutation of known “deleterious” consequence or one of “uncertain significance?”..."
jimmyf1963 | @jimmyf1963 | Aug 18 9:09am

I have a deleterious mutation. A sibling was diagnosed with pancreatic cancer at 51 and tested positive for a BRCA2 mutation. I don't have a urologist since moving to Florida almost two years ago, but have an appointment with my PCP this week and will discuss it with him.
Also starting a pancreatic cancer screening program at Moffitt so I will ask the genetic counselor about seeing a urologist there. Can you ask your doctor for the MRI?
Never had a problem with my prostate, but I do have a urethral stricture that affects my urination.

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