I had a Reclast infusion in 2018 with no side effects. I had a second infusion on Thursday, August 1 of this year, one month after completing a year of Evenity. That night, I began to feel distressed. By 4:00am, I had a temperature of 101. I continued to have spiking temperatures as high as 103.2 despite taking Tylenol. I was so weak I could barely make it to the bathroom. Couldn’t eat or drink, slept when I could. By Sunday afternoon, I agreed to go to the ED. I was admitted with fever, tachycardia to 120, low BP (85/54). Labs showed anemia, hypokalemia and lowered electrolytes. Other symptoms included episodes of profuse sweating, coughing that was painful to the lungs, labored breathing (O2 at 85) and blurred vision. The docs thought the Reclast was a red herring and that I had a viral upper respiratory infection, due to having a chronic lung condition. I was treated with two IV antibiotics, IV fluids, and Tylenol and discharged with a 14-day prescription of oral antibiotics the following Wednesday. Today, 16 days after the infusion, my temperature is almost normal at 97.2 (by baseline is 96.8). My body is relaxed and I’m enjoying food again. Still tire easily, am fatigued going upstairs and sitting to floss. Because I developed anemia, I Googled Reclast and anemia and found a very long list of side effects. I identified 22. I have no doubt that this acute event was caused by the Reclast.

So what I’m wondering @heartfelt, did the Reclast still prevent bone loss for you, even though you had an adverse reaction? Also wondering what you and your docs decided on treatmentwise since then.

Regarding resolution, I’m drinking a lot of electrolyte water, and will go to the gym for paced treadmill walking and easy leg press to begin to gain strength. Thank you all for sharing and thanks @dingus for posting the question.