Aching ankles and calves

@silvern12, I think pain in the calves when you have neuropathy is not uncommon. Many members have shared their experiences in different discussions. Here's a link that shows the discussions and comments - https://connect.mayoclinic.org/search/?search=pain+in+calves+%2Bneuropathy.

It's good that you have discussed the pain with your cardiologist to insure it's not caused by a blood clot. I'm assuming the pain you are describing in your calves is not related to exercise but here is an article that discusses possible causes.
-- Calf pain: 9 causes, treatment, and stretches: https://www.medicalnewstoday.com/articles/321446

Did your cardiologist provide any suggestions or thoughts on possible causes?

Hello, @silvern12. My ankles and calves often ache, especially in the early morning and late evening. My PN is idiopathic, predominantly large fiber polyneuropathy. I've been contending with it for years. Recently, I was found to have a blood infection (sepsis). I'm almost rid of all traces of the infection, but the recovery has taken over four months. I mention both conditions––my PN and the sepsis infection––because the combination of the two has kept me from getting even reasonable exercise. My wound care doctor and home health nurse tell me that the aches in my ankle and calves are almost certainly due to this reduced exercise and not a presentation of either of my two conditions, neither my PM nor sepsis infection. As PT helps to rebuild my lower body strength, I've noticed my ankles and calves are less and less achy. Good luck to you in your search for an answer to––and relief from––the achiness that you are feeling. Cheers! ––Ray (@ray666)

It has a lot to do with getting enough exercise for me. If I am not able to walk outside, I'll walk indoors. That stretch really works too.

Go to gym every day very active work through the pain but aching never ends going to neurologist then pain dr and vein specialist to try to get snswers

If you have length-dependent small fiber neuropathy (I do) it progresses in a stocking-and-glove pattern. Biopsies on my legs confirmed my diagnosis.

I have burning pain in the back of my calves which are also warm to the touch.

This only happens at night in bed.

I had ILC BC and radiation and now Letrozole for 17 months.

I am now off Letrozole for a few weeks. Am at one week off point and still have this pain.

Early on, the breast surgeon said that this was not cardiac but caused by the Letrozole.
If I stay in bed when I wake up, the pain then goes to the heel and down to middle of foot and the Achilles’ tendons both hurt.

Is this neuropathy? I did not have chemotherapy.

Some days, both Achilles’ tendons hurt and swell in the daytime.

What is your potassium level?