@bilchar2 they "should" go away in 2 - 3 months (says my doctors/team) at UCSD. They did for me. I had to stop after one month and titrate up (start again at a lower dose and work up). Your body will adapt. You should ask your doctors ahead of time about the side effect possibilities and them for links to reading materials. Things like knowing to take the medicine at night so you sleep the fatigue off, and having anti-nausea meds if you get queasy - I did when I injected in the morning. I had light headaches for a month. Everything went away, like they said! (you can always stay on a lower dose if need be). Drink plenty of fluids.