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Metformin side effects

Diabetes & Endocrine System | Last Active: Oct 13 12:20pm | Replies (31)

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@naiviv

Hello. I know that Metformin causes lots of side effects but has anyone experienced waking up with no appetite at all and no matter if breakfast is eaten still the loss of appetite continues all day? I take 500 mg ER after breakfast. Also have your doctors mentioned that Vit B12 might be affected by Metformin in lowering it a lot. Vit B12 is essential for muscles, cognitive and red blood cells. Thank you

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Replies to "Hello. I know that Metformin causes lots of side effects but has anyone experienced waking up..."

@naiviv ,
I haven’t been on the connect.mayoclinic website in a few months, so when I clicked on today the first post I saw was yours. I visited the site today trying to find some insight on the blood test results I got yesterday. I am also on metformin 2x a day after meals. I was in shock by the results of my B12 test, I was not on the low end, but rather almost 3000 points higher than the highest end of the acceptable range. I wish I had a loss of appetite, but the only other side effect for me is severe constipation. Amazing how the same drug can have such opposite effects. Just for reference,
I was diagnosed almost 1 year ago at the age of 67.

I was put on metformin without any explanation as to why. I had had appendicitis and was sent home with metformin.....(5 years later developed diabetes!) after a few days I began to lose my appetite and it finally got to the point where I couldn't even have a cup of soup.