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Anyone had cancer return while taking hormone therapy meds?

Breast Cancer | Last Active: Nov 16 9:03pm | Replies (242)
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@vegada

I had the BCI test when I hit 4 years of being on Anastrozole and I was stage 1. The challenge with the BCI test is it doesn't stratify between stage 1 and stage 2 I was told. So some Drs wont even order the BCI test for Stage 1. My Dr ordered it and it showed I would benefit from staying on an extra 5 years and would reduce my recurrence by another 50%. So I don't really know how to interpret this result given I was told the test doesn't stratify the results between stage 1 and stage 2. Has anyone else ever heard this?

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Replies to "I had the BCI test when I hit 4 years of being on Anastrozole and I..."
windyshores | @windyshores | Aug 11 9:02am

@vegada not sure what you mean by stratifying between stage 1 and 2. I thought Oncotype didn't either. My BCI gave me a yes or no answer about whether to continue an AI (in my case no) and also gave an assessment of recurrence risk after 5 years w/ a percentage number (high for me). It uses tissue from our original tumor. I had lympohvascular invasion and none of the genomic tests take that into account.

"Breast Cancer Index® (BCI) is the only test recognized by the NCCN Clinical Practice Guidelines in Oncology (NCCN® Guidelines) and the ASCO® Clinical Practice Guideline to predict which patients are likely to benefit from extension of adjuvant anti-estrogen therapy beyond 5 years.1,2"

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