Oncotype below 15, but cancer returned

Posted by Rom828 @jgallagher04921, Aug 3 6:09am

Anyone told they had a low risk of cancer returning, but it did return? If so, how much time passed between diagnosis?

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@rosa1935

My breast cancer was stage 3 and hadn’t spread to the lymph nodes

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My Oncotype was 29 as well but I was stage 1. The mammaprint test was low risk. So I had one genomic test saying 29(higher risk of recurrence) and the other genomic test(Manmaprint) showing low risk. They are different tests but mammaprint rests for more than Oncotype does yet they issued totally different overall recurrence risk stats.

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@cashemire

@colely Do you know if they consider this a recurrence or a new cancer?
Sending warm thoughts that all goes well! Had you stopped the Tamoxifen given the symptoms? I had local recurrence after 2.5 yrs (rad but no AI) and was oncotype 10.

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I found out today that the new cancer in my left brest is called a second primary cancer. I can't tolerate tamoxifen. I can't take A.I.s because of osteoporosis. I can't do radiation because of tricuspid valve regurgitation from EDS, and heart arythmia that can be triggered by neurotoxin pesticides and certain medications, such as Imitrex.

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@colely

I found out today that the new cancer in my left brest is called a second primary cancer. I can't tolerate tamoxifen. I can't take A.I.s because of osteoporosis. I can't do radiation because of tricuspid valve regurgitation from EDS, and heart arythmia that can be triggered by neurotoxin pesticides and certain medications, such as Imitrex.

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@colely I had pretty serious osteoporosis and still did an aromatase inhibitor. I did not do Reclast or Zometa, that most people do to protect bones, because at the time it was thought those bone drugs could exacerbate my afib. That is not longer a concern.

I lost more bone and fractured 7 years after my cancer diagnosis and two years after stopping letrozole- but only because 1) I made an extremely unwise movement and 2) COVID delayed my treatment.

Two years of Tymlos improved by spinal bone density back to better than it was before cancer.

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