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Prostate cancer radiation failed

Prostate Cancer | Last Active: Aug 10 2:29pm | Replies (59)

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@scottbeammeup

I hope you're right about RNA. Right now I'm reading "The Emperor of All Maladies." It's the history of cancer and treatment and it seems we've been stuck on chemo and radiation for almost a century now. It's more refined but it's the same basic treatment.

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Replies to "I hope you're right about RNA. Right now I'm reading "The Emperor of All Maladies." It's..."

Good points (and for prostate cancer, add ADT as the third "old school" treatment, dating back to the 1940s I think).

Fortunately, things have changed a lot since your book came out in 2010. Second-gen ARSIs arrived just before the pandemic (Erleada, which I'm on, was approved around 2018), and they've been game changers.

If/when things progress, a common option is Pluvicto: it is still technically radiation, but can target widely-scattered cancer, which traditional external radiation can't. And there are immunotherapies and all kinds of other treatments.

In 2010 our path forward for metastatic prostate cancer was usually ADT ➡️ radiation ➡️ chemo ➡️ "I'm so sorry, there's nothing else we can do."

Now my RO gets so excited that he sounds like a kid in a candy shop talking about all the new treatment options available if my current ADT+ARSI stops working. He also says it could be 10+ years before that happens. More here:
https://www.scientificamerican.com/article/treating-prostate-cancer-at-any-stage/