Lanreotide and blood pressure

Hi @rogerstc, according to this article about Lanreotide from Mayo Clinic
"This medicine may increase your risk for heart and blood vessel problems, including hypertension and a slow heartbeat. This may cause chest pain or discomfort, headaches, dizziness, or blurred vision. You might need to measure your blood pressure at home. If you think your blood pressure is too high or if your heartbeat is too slow, call your doctor right away."
Read more here https://www.mayoclinic.org/drugs-supplements/lanreotide-subcutaneous-route/precautions/drg-20071321#:~:text=This%20medicine%20may%20increase%20your%20risk%20for%20heart%20and%20blood,your%20blood%20pressure%20at%20home.

@gsm13161 @allan2022 @gneiss50 @californiazebra @ginnyos @amandafl may have experiences to add.

Roger, did you talk to your oncologist about your blood pressure? What is being suggested?

Octreotide lowered my blood pressure and heart rate. Also causes fatigue.

Hi Rogerstc

I am on my 12th Lanreotide injection (120ml). I just recently discovered that my blood pressure increased quite significantly. I will talk with my Oncologist at my next meeting but it would be grate if anyone can share their journey on how to manage blood pressure.

I am on Lanreotide - but bp lowered too. Stopped taking bp meds and started taking Electrolyte supplements daily and that seems to help me. Electrolit Zero is the drink I tend to use. Zero sugar bc sugar feeds the cancer cells???

I am asking my primary care doctor the same question today. I will get back to you with whatever he decides. My question for him is what lead me to Mayo Clinic and an article listing medications you shouldn't take with Lanreotide. It is best for you to talk to your primary and ask them if you need bp meds. I had always been on a mild bp med prior to my first diagnosis, a second med was added when the cancer returned and the Lanreotide appeared to be raising my bp. Then I got Covid bc life is funny that way, and my bp dropped terribly - I stopped both bp meds. Now I am rehydrated and feeling better but my heart is racing again and bp is up not terribly but enough that I think I may need to go back on a maintenance drug. I use the Drug.com site to list all of my meds and conditions. It will tell you if there are any interactions but I wish Mayo Clinic or another site would have an option to do that for neuroendocrine cancer patients. Stay strong! My best advice is to have a Primary Care Doctor and have your cancer team share all records and results with them. No matter how great your oncologist is, they are focused on your cancer, not as much on the side effects of the treatment. A primary will help you with everything else. I also have a pain mgt doctor that was great after my first surgery. I was still in so much pain and he was the only one that explained that even though my incision had healed on the surface, there were dissolvable stitches made beneath them to pull my abdominal muscles back in place and they take longer to heal. You need them on your team. Stay Strong!

My oncologist referred me to my primary care doctors. He eventually switched my bp meds because the one i was taking interacted with Lanreotide. Bp numbers are now normal.

Hello @joneshome and welcome to the NETs support group on Mayo Connect. I appreciate you sharing your experience with Lanreotide. From your post, it appears that you have had one surgery and a recurrence.

As you are new to this forum, please share, as you are comfortable doing so, a little about your journey with NETs. For example, how long ago were you diagnosed. How are you feeling now?

I look forward to hearing from you.

According to the Mayo Clinic, it's a myth that sugar feeds cancer cells and makes them grow faster. In fact, research shows that depriving cancer cells of sugar doesn't make them grow more slowly either. However, cancer cells do absorb more glucose than other tissues because they use more energy, and they use a different chemical process to make energy from glucose. This can lead to cancer cells craving sugar.

Yes, I have the Lanreotide high blood pressure situation. I take Amlodipine and Losartan daily to combat it. I was also prescibed Metoprolol, but that causes ED issues for me, LOL. That ain't cool. SO at the present time I'm sticking with the other two meds. It is a challenge for me to keep the BP in check. Walking daily, eating a balanced diet, + keeping weight reasonable all contributes to lower BP for me just like everybody else. My problem is driving in downtown traffic, hiking a half mile to the hospital, then sitting for a BP check! It's gonna be high, I'm not resting. 🙂