Has anyone else noticed the skin on their upper arms loose and wrinkly? I am 66 and my upper arms have no muscle tone, sagging and wrinkly skin. My arms look like that of a 90 year old. This change has occurred in the past year. My arms were not like this last summer. I feel embarrassed to wear short sleeves. I have always used hand weights in my workout twice weekly, so I know it’s not that. I guess it’s the prednisone. But I have been taking no more than 8 mg in the past year and now down to 3. Could this be the prednisone? And if it is, what are the chances the skin on my arms will tighten up again?