Hi Brandy: I had my visual by my gynecologist and she said that this time around I did not have a manifestation of Paget of the Vulva like I had a year ago and two years before that. I have to go back every six months for the rest of my life. So, I appreciate a break this time. She seemed to think that I was responding well to Imiquimod. I did recall reading your text that the second time, last year, that I did not have the burning and the itching was not bad and I remember that I also thought maybe the cream was not working well. But it did, so maybe that will help you. So, I am taking it one day at the time. I think more and more we will see new cases of this disease and maybe that will excite researchers into researching new medications or procedures... Let's hope.. Let's keep in touch